Cerium oxide nanoparticle therapy for diabetic wounds
Despite the current therapies for chronic wounds in diabetic patients, a significant number of wounds fail to heal. In this study, our researchers targeted two key aspects of non-healing diabetic wounds – chronic inflammation and high oxidative stress – by applying cerium oxide nanoparticles (CNP) as a novel therapeutic agent. Our data showed that local treatment of the diabetic wound with CNP-miR146a resulted in improved healing of diabetic wounds without impairing the biomechanical properties of the skin post-healing. This demonstrates that CNP-miR146a therapy has potentially far-reaching implications for diabetic wound healing research.
Read our article "Use of Cerium Oxide Nanoparticles Conjugated with MicroRNA-146a to Correct the Diabetic Wound Healing Impairment"